Salmon-derived PN Booster, Endranhiller

Unique Features of Endran Healer

1. Same Ingredients, Reasonable Treatment Cost

Utilizing salmon-derived PN ingredients, similar to RejXran, you can expect skin improvement while reducing the financial burden.

2. Systematic Treatment Beyond Simple Injection

By thoroughly analyzing the skin structure and injecting PN ingredients into the appropriate layers and depths, we help achieve satisfactory improvements.

3. Confirming Treatment Accuracy Through Wheal Formation

Immediately after the treatment, we confirm the wheal formation on the skin with the patient, ensuring that the medication has been properly delivered to the intended area.

4. Direct Supervision by Medical Staff from Consultation to Treatment

After carefully diagnosing the patient's skin condition and past treatment history, our medical staff directly provides a careful 1:1 customized treatment.

5. Reduces Irritation and Supports Comfortable Recovery.

By using Jaungo modeling pack, we help reduce irritation and soothe even sensitive skin after the procedure, assisting in a comfortable calming process.

6. Precise Control of Wheal Spacing by Skin Area

Wheal spacing is adjusted according to the characteristics of each facial area. For cheeks and forehead, the spacing is set for improvement, while around the eyes and mouth, it can be applied more delicately and densely. This treatment precisely controls the spacing, considering skin thickness, elasticity, and even the direction of wrinkles.

Reasons to Consider Endran Healer

1. Same Ingredients, Smart Choice

As the patent for PN (Polynucleotide), the key ingredient of RejXran, has expired, various products containing similar salmon-derived PN ingredients are being launched.

Endran Healer also contains these same ingredients,

and you can receive treatment at a more reasonable cost.

As a practical PN treatment that promotes skin improvement while reducing the financial burden,

if you are considering a cost-effective PN treatment, Endran Healer can be an option.

2. Precision of Treatment, as Important as the Ingredients

Even with the same PN ingredients, treatment results may vary individually.

Endran Healer treatment goes beyond simple injection,

and is performed by precisely calculating the skin tissue layers, depth, and necessary injection volume.

We meticulously assess the patient's skin thickness, degree of damage, pore structure, etc., to adjust the depth appropriate for each layer.

This precision can positively influence dermal remodeling and collagen regeneration.

3. Confirming Treatment Accuracy Through Wheal Formation

The medical staff confirms whether the PN ingredients have been injected into the intended location

by visually checking with the patient.

Generally, wheal formation is a temporary reaction and is considered an important indicator that the medication has been well injected into the planned dermal layer.

Therefore, after the treatment, we examine the wheal formation with the patient to check the injection status.

Thus, checking for wheal formation is an important process considered for treatment accuracy and satisfactory results.

4. Customized Consultation and Treatment Directly Performed by Medical Staff

At our medical institution, instead of mechanical explanations from a consultation manager, our medical staff directly communicates with the patient and provides necessary information.

Our medical staff directly assesses and consults on various factors such as the patient's current skin condition, sensitivity, past treatment experience, and skincare products being used,

throughout the entire process.

This can positively influence the more effective action of PN ingredients,

and can help reduce the possibility of unnecessary inflammatory reactions or unexpected situations.

5. Post-Treatment Irritation Reduction and Comfortable Recovery Management

After PN treatment, a Jaungo modeling pack is fundamentally included to help soothe and recover the skin.

We provide a complex traditional Korean calming treatment to quickly soothe skin heat, redness, and sensitivity.

This can prevent excessive immune responses from occurring in the skin.

This is precisely why PN treatment can be considered without burden, even for thin or sensitive skin.

We provide meticulous care that covers the entire recovery process after the procedure.

6. Customizable injection interval according to area

When performing Endranhiller treatment, we meticulously plan not only the injection points but also the injection intervals.

For example, in areas like the cheeks or forehead, where the dermis is relatively thick and wide,

Even if the PN component is injected at a single point, it spreads widely, so sufficient improvement can be expected with a 1~1.5cm interval.

However, around the eyes and mouth, the skin is thin and wrinkles are concentrated,

precise injections at 0.5cm intervals are necessary to effectively refine the skin texture.

If the skin is thin and there are many sunken areas,

or if the skin texture has become irregular due to lasers or other treatments, even areas like the cheeks or forehead are adjusted to receive more dense injections.

Considering skin thickness, elasticity, wrinkle direction, and the desired outcome of the treatment,

we perform 1:1 individualized design, customizing the injection points and intervals to each patient.

Even with the same 2cc or 4cc volume, different results can be expected depending on the treatment method.

Thus, customized treatment, rather than mechanical injection, is one of Endranhiller's unique characteristics.

Endranhiller, what are its effects?

1. Firmer skin through collagen & elastin production

The PN (Polynucleotide) component extracted from salmon activates fibroblasts in the skin's dermal layer,

aiding in the production of collagen and elastin.

→ This is expected to improve skin thickness, reduce fine lines, and restore elasticity.

Furthermore, pore improvement can also be expected.

2. Restoring damaged skin barrier and strengthening self-regenerative power

PN promotes the secretion of growth factors like TGF and FGF, contributing to epidermal cell regeneration and skin barrier recovery.

→ This can help reduce inner dryness, alleviate skin sensitivity, and enhance the skin's inherent recovery power.

It has a particularly positive effect on accelerating the recovery of sensitive skin after laser treatments or peeling.

3. Naturally improved skin condition

Endranhiller is not a treatment that fills volume like a filler or blocks muscle movement like Botox.

→ After the treatment, the skin regains its natural healthy strength, becoming smoother in texture, experiencing less inner tightness, and allowing makeup to absorb better.

If you desire clear skin changes that are not overtly noticeable, consider Endranhiller.

Endranhiller Principle

1. Reorganizing skin structure through fibroblast activation

The main component of Endranhiller, PN (Polynucleotide),

is a high-purity DNA fragment derived from salmon, which, when injected into the skin,

acts similarly to a wound response, stimulating fibroblasts.

These fibroblasts produce collagen, elastin, hyaluronic acid, etc.,

playing a key role in rebuilding the skin to be thicker and more elastic.

2. Enhancing skin's regenerative power through growth factor secretion

Activated fibroblasts secrete various growth factors.

TGF-β: Promotes collagen synthesis

FGF components help the regeneration process of skin cells and promote the recovery of damaged areas.

VEGF helps to smooth microcirculation in the skin, aiding in nutrient supply.

These growth factors contribute to creating a regenerative environment for healthy skin.

This can help the epidermal layer and skin barrier to regain their functions naturally.

As a result, skin sensitivity can be reduced, inner dryness alleviated, and overall restorative power enhanced.

3. Improved dermal density can enhance skin elasticity.

Endranhealer affects the dermis, a crucial part of the skin.

PN components contribute to reorganizing the structure of the extracellular matrix (ECM). (The extracellular matrix is an important substance that makes up the dermal layer.)

This process helps collagen, hyaluronic acid, and various proteins to more firmly support dermal tissue.

As a result, you can expect your skin to feel firmer, sunken areas to improve, skin texture to become smoother, and makeup to blend better.

4. Minimizes irritation, promotes recovery, and offers anti-inflammatory effects.

PN components not only aid in skin regeneration but can also regulate micro-inflammatory responses within the skin.

Persistent redness

Sensitive skin that reacts easily to external stimuli

Sensitivity appearing after laser treatment

Even in such sensitive conditions, it can help calm unnecessary inflammatory responses and guide healthy skin recovery processes.

Therefore, Endranhealer is a PN treatment that can be considered by those with delicate or sensitive skin.

Endranhealer Treatment Procedure

1. Skin Condition Analysis

By thoroughly assessing the patient's skin thickness, elasticity, and sensitivity,

we carefully determine the appropriate depth and method for PN injection.

2. 1:1 Consultation with Medical Staff

The medical team directly and thoroughly diagnoses the skin areas requiring improvement and the overall treatment area,

and establishes a customized plan.

We create a treatment plan optimized for each individual's skin characteristics, rather than a standardized approach.

3. Anesthetic Cream Application

Since PN components are directly injected into the dermal layer,

we allow a sufficient numbing time of about 20 to 30 minutes

to minimize any discomfort that may occur during the procedure.

4. Endranhealer Injection Procedure

PN components are carefully injected into the pre-planned depth and areas.

The treatment location is immediately confirmed through the 'emboss' phenomenon that appears upon injection,

and fine adjustments are made immediately if necessary to enhance the precision of the procedure.

5. Jaurungo Modeling Pack Soothing Step

Immediately after the procedure, a Jaurungo Modeling Pack is used to

quickly alleviate skin irritations such as needle marks, redness, and heat sensation.

This helps prevent excessive immune responses and allows the skin to begin a comfortable recovery.

Endranhealer Recommended Treatment Intervals and Duration

1. Initial Intensive Treatment (Total 3 sessions)

We generally recommend receiving a total of three treatments at one-month intervals.

There's a clear reason for this treatment process.

The PN components need to accumulate sufficiently in the dermis layer,

which effectively stimulates fibroblasts,

allowing for stable collagen remodeling to be induced.

2. Maintenance for Treatment Efficacy

If you wish to maintain your improved skin condition for a long time after the procedure,

you can generally consider touch-up treatments every 6 months to 1 year.

While there may be individual differences depending on skin characteristics or lifestyle habits,

you can expect the effects to last approximately 6 to 12 months after completing the recommended 3 sessions.

3. How long do the effects last after the procedure?

Once the collagen remodeling process in the skin is complete,

improvements in skin texture, elasticity, and density can generally be maintained for 6 months or more.

However, the duration of maintenance may be shortened by several factors:

If the skin is excessively thin or highly damaged,

or if there are lifestyle habits that continuously stress the skin, such as smoking or strong UV exposure.

4. When do the effects become apparent?

Immediately after the procedure, some embossing or mild swelling may be observed.

About 1 week after the procedure, you may notice that makeup applies better or your skin feels smoother.

By weeks 2-3, improvements in elasticity and skin density may appear, and fine wrinkles may be alleviated.

After completing all 3 recommended sessions, the positive changes in the internal skin structure become even more pronounced, giving a strong feeling of skin improvement.

How much pain is involved with Endranhiller treatment?

You may feel a tolerable level of stinging.

Since PN components are injected into the dermis layer, it is not completely painless,

but sufficient anesthesia is provided to help most patients receive the treatment comfortably.

Differences in pain by treatment area

You may feel little to no sensation around the cheeks, forehead, and mouth.

You may feel a momentary sting around the eyes, bridge of the nose, and chin.

A dull pressure may be felt in areas with large pores.

Efforts to reduce pain during treatment

Sufficient time is allowed after applying anesthetic cream.

During the procedure, the injection speed is slowed, and small amounts are delicately injected.

The patient's pain response is monitored in real-time.

After the procedure, a soothing pack is used to stabilize the skin.

Those considering Endranhiller treatment

1. Those concerned about many fine wrinkles

If you have dense fine wrinkles around the eyes, cheeks, or mouth,

this may be suitable for those who find lifting or filler treatments burdensome but desire natural wrinkle reduction.

2. Those with sensitive skin that easily becomes red

Recommended for those whose skin reacts sensitively to cosmetic changes or frequently experiences flushing,

and who wish to strengthen damaged skin barriers to restore healthy skin.

3. For those with inner skin dryness and makeup that doesn't sit well

This applies if your skin's surface is oily, but you feel dryness and tightness deep within, and your makeup often cakes or doesn't adhere well.

It may be suitable for dehydration-prone skin where you continue to feel tightness deep within, even after using external moisturizing products.

4. For those with skin sensitized by frequent procedures

Your skin might have become thinner or more sensitive from repeatedly undergoing procedures like lasers or peels.

You might consider it if you wish to strengthen your skin's fundamental healing and regenerative capacity.

5. For those seeking to improve skin density and texture

This is when your skin's elasticity has decreased, leading to a generally sagging appearance and a feeling of lacking density.

It is especially recommended for those who feel their cheekbone or cheek contours appear less defined, and their skin texture feels uneven.

Embossing Phenomenon After Endran Hiller Treatment

After undergoing Endran Hiller treatment, you might temporarily notice small, raised bumps, resembling an embossing effect, in the treated area.

This embossing can be considered a positive sign, indicating that the injected solution has been effectively delivered to the skin's dermal layer.

It is a normal reaction for the skin to feel slightly lumpy or bumpy, and it is also a sign that you can anticipate the treatment's positive effects.

In most cases, the embossing will naturally subside within 1 to 2 days after the procedure.

For individuals with thinner or drier skin, it may last around 2 to 3 days, and in sensitive areas like around the eyes or mouth, it might persist for up to 4 days.

Rarely, the embossing might remain for 5 to 7 days or even longer, but

if it's not accompanied by symptoms such as pain, warmth, or severe redness, you generally do not need to be overly concerned.

This can even be interpreted as a positive sign that the solution is being slowly absorbed, allowing it to work effectively for a longer duration.

Post-Treatment Precautions

• A bumpy sensation, redness, or mild pain in the treated area may persist for 2 to 3 days after the procedure.
• Bruising, tiny needle marks, and swelling may last approximately 1 to 2 weeks after the procedure.
• For approximately 7 days after your treatment, it is advisable to avoid activities that could irritate the skin, such as consuming alcohol, smoking, visiting saunas or swimming pools, and engaging in strenuous exercise.
• After your treatment, please prioritize moisturizing to soothe your skin, and always apply sunscreen thoroughly when going outdoors.